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Contributors
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- By Aakash Agarwala, Linda S. Aglio, Rae M. Allain, Paul D. Allen, Houman Amirfarzan, Yasodananda Kumar Areti, Amit Asopa, Edwin G. Avery, Patricia R. Bachiller, Angela M. Bader, Rana Badr, Sibinka Bajic, David J. Baker, Sheila R. Barnett, Rena Beckerly, Lorenzo Berra, Walter Bethune, Sascha S. Beutler, Tarun Bhalla, Edward A. Bittner, Jonathan D. Bloom, Alina V. Bodas, Lina M. Bolanos-Diaz, Ruma R. Bose, Jan Boublik, John P. Broadnax, Jason C. Brookman, Meredith R. Brooks, Roland Brusseau, Ethan O. Bryson, Linda A. Bulich, Kenji Butterfield, William R. Camann, Denise M. Chan, Theresa S. Chang, Jonathan E. Charnin, Mark Chrostowski, Fred Cobey, Adam B. Collins, Mercedes A. Concepcion, Christopher W. Connor, Bronwyn Cooper, Jeffrey B. Cooper, Martha Cordoba-Amorocho, Stephen B. Corn, Darin J. Correll, Gregory J. Crosby, Lisa J. Crossley, Deborah J. Culley, Tomas Cvrk, Michael N. D'Ambra, Michael Decker, Daniel F. Dedrick, Mark Dershwitz, Francis X. Dillon, Pradeep Dinakar, Alimorad G. Djalali, D. John Doyle, Lambertus Drop, Ian F. Dunn, Theodore E. Dushane, Sunil Eappen, Thomas Edrich, Jesse M. Ehrenfeld, Jason M. Erlich, Lucinda L. Everett, Elliott S. Farber, Khaldoun Faris, Eddy M. Feliz, Massimo Ferrigno, Richard S. Field, Michael G. Fitzsimons, Hugh L. Flanagan Jr., Vladimir Formanek, Amanda A. Fox, John A. Fox, Gyorgy Frendl, Tanja S. Frey, Samuel M. Galvagno Jr., Edward R. Garcia, Jonathan D. Gates, Cosmin Gauran, Brian J. Gelfand, Simon Gelman, Alexander C. Gerhart, Peter Gerner, Omid Ghalambor, Christopher J. Gilligan, Christian D. Gonzalez, Noah E. Gordon, William B. Gormley, Thomas J. Graetz, Wendy L. Gross, Amit Gupta, James P. Hardy, Seetharaman Hariharan, Miriam Harnett, Philip M. Hartigan, Joaquim M. Havens, Bishr Haydar, Stephen O. Heard, James L. Helstrom, David L. Hepner, McCallum R. Hoyt, Robert N. Jamison, Karinne Jervis, Stephanie B. Jones, Swaminathan Karthik, Richard M. Kaufman, Shubjeet Kaur, Lee A. Kearse Jr., John C. Keel, Scott D. Kelley, Albert H. Kim, Amy L. Kim, Grace Y. Kim, Robert J. Klickovich, Robert M. Knapp, Bhavani S. Kodali, Rahul Koka, Alina Lazar, Laura H. Leduc, Stanley Leeson, Lisa R. Leffert, Scott A. LeGrand, Patricio Leyton, J. Lance Lichtor, John Lin, Alvaro A. Macias, Karan Madan, Sohail K. Mahboobi, Devi Mahendran, Christine Mai, Sayeed Malek, S. Rao Mallampati, Thomas J. Mancuso, Ramon Martin, Matthew C. Martinez, J. A. Jeevendra Martyn, Kai Matthes, Tommaso Mauri, Mary Ellen McCann, Shannon S. McKenna, Dennis J. McNicholl, Abdel-Kader Mehio, Thor C. Milland, Tonya L. K. Miller, John D. Mitchell, K. Annette Mizuguchi, Naila Moghul, David R. Moss, Ross J. Musumeci, Naveen Nathan, Ju-Mei Ng, Liem C. Nguyen, Ervant Nishanian, Martina Nowak, Ala Nozari, Michael Nurok, Arti Ori, Rafael A. Ortega, Amy J. Ortman, David Oxman, Arvind Palanisamy, Carlo Pancaro, Lisbeth Lopez Pappas, Benjamin Parish, Samuel Park, Deborah S. Pederson, Beverly K. Philip, James H. Philip, Silvia Pivi, Stephen D. Pratt, Douglas E. Raines, Stephen L. Ratcliff, James P. Rathmell, J. Taylor Reed, Elizabeth M. Rickerson, Selwyn O. Rogers Jr., Thomas M. Romanelli, William H. Rosenblatt, Carl E. Rosow, Edgar L. Ross, J. Victor Ryckman, Mônica M. Sá Rêgo, Nicholas Sadovnikoff, Warren S. Sandberg, Annette Y. Schure, B. Scott Segal, Navil F. Sethna, Swapneel K. Shah, Shaheen F. Shaikh, Fred E. Shapiro, Torin D. Shear, Prem S. Shekar, Stanton K. Shernan, Naomi Shimizu, Douglas C. Shook, Kamal K. Sikka, Pankaj K. Sikka, David A. Silver, Jeffrey H. Silverstein, Emily A. Singer, Ken Solt, Spiro G. Spanakis, Wolfgang Steudel, Matthias Stopfkuchen-Evans, Michael P. Storey, Gary R. Strichartz, Balachundhar Subramaniam, Wariya Sukhupragarn, John Summers, Shine Sun, Eswar Sundar, Sugantha Sundar, Neelakantan Sunder, Faraz Syed, Usha B. Tedrow, Nelson L. Thaemert, George P. Topulos, Lawrence C. Tsen, Richard D. Urman, Charles A. Vacanti, Francis X. Vacanti, Joshua C. Vacanti, Assia Valovska, Ivan T. Valovski, Mary Ann Vann, Susan Vassallo, Anasuya Vasudevan, Kamen V. Vlassakov, Gian Paolo Volpato, Essi M. Vulli, J. Matthias Walz, Jingping Wang, James F. Watkins, Maxwell Weinmann, Sharon L. Wetherall, Mallory Williams, Sarah H. Wiser, Zhiling Xiong, Warren M. Zapol, Jie Zhou
- Edited by Charles Vacanti, Scott Segal, Pankaj Sikka, Richard Urman
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- Essential Clinical Anesthesia
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- 05 January 2012
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- 11 July 2011, pp xv-xxviii
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Chap. 32 - EMERGENCY MANAGEMENT OF SKIN TORTURE AND SELF-INFLICTED DERMATOSES
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- By Daniel H. Parish, Jefferson Medical College of Thomas Jefferson University, Hirak B. Routh, Paddington Testing Company, Inc., Kazal R. Bhowmik, Paddington Testing Company, Inc., Kishore Kumar, Dhaka Medical College Hospital
- Edited by Ronni Wolf, Batya B. Davidovici, Jennifer L. Parish, Lawrence Charles Parish
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- Emergency Dermatology
- Published online:
- 07 September 2011
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- 17 January 2011, pp 313-317
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Summary
TORTURE WRIT broadly is the intentional infliction of physical or psychological pain. The term includes a wide variety of conduct ranging from that instigated by authorities to gain confessions or information to that caused by private actors in the course of domestic abuse or in the intimidation of neighbors or disliked ethnic or religious minorities. Most legal definitions of torture, however, restrict its definition by requiring an element of state action. Thus, for example, the United Nations Convention against Torture defines it as:
any act by which severe pain or suffering, whether physical or mental, is intentionally inflicted on a person for such purposes as obtaining from him or a third person information or a confession, punishing him for an act he or a third person has committed or is suspected of having committed, or intimidating or coercing him or a third person, or for any reason based on discrimination of any kind, when such pain or suffering is inflicted by or at the instigation of or with the consent or acquiescence of a public official or other person acting in an official capacity. It does not include pain or suffering arising only from, inherent in or incidental to lawful sanctions.
Similarly, the damage done by torture and the evidence of the same range widely. On the one hand, some persons torturing others seek to injure their victims in a way that is highly visible and consequently damaging to the victim's psyche (and serve as a threat to anyone who sees the victim).
Further Observations on the Persistence of Larvicides against Culicoides and a Discussion on the Interpretation of Population Changes in the untreated Plots
- D. S. Kettle, R. H. Parish, Jean Parish
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- Journal:
- Bulletin of Entomological Research / Volume 50 / Issue 1 / March 1959
- Published online by Cambridge University Press:
- 10 July 2009, pp. 63-80
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This paper presents further observations on the continued persistence of larvicidal treatments applied to small plots (10 yd. × 10 yd.) on Soutra Hill, Midlothian, to control larvae of the biting midge, Culicoides impunctatus Goetgh. Before doing so, consideration is given to the nature of the observed fluctuations in larval population encountered in the untreated plots. Evidence is produced which indicates that this is not due either to delayed hatching of eggs (this, if it occurs, is of minor importance), to change in technique or to the application of insecticide to neighbouring plots, but is due to the larvae responding to an oscillating factor (or factors) in the breeding site. It is suggested that one such factor might be soil water level. Therefore, it follows that changes in the untreated larval population must be taken into account when assessing the degree of control achieved by treatments, especially when the larval population is declining.
As regards insecticidal persistence three years after application: —
(i) Nine of the eleven DDT treatments (wettable powder, water-miscible concentrate and dust at 12, 50 and 200 mg. p,p′DDT/sq. ft.) gave 100 per cent. control. The other two (both wettable powder at 12 mg./sq. ft.) produced 75 and 22 per cent. reduction.
(ii) Only one of seven γ BHC treatments (wettable powder at 50 mg. γ BHC/sq. ft.) gave complete control and one treatment (w.p. 12 mg./ sq. ft.) was completely ineffective.
(iii) DDT retained its superiority to γ BHC as a larvicide against Culicoides, achieving 93 per cent. control compared with 55 per cent. for γ BHC.
(iv) The lowest dosages of dieldrin (3 mg./sq. ft.) and chlordane (6 mg./ sq. ft.) had begun to lose their larvicidal power, control declining from 76 to 53 per cent. and 67 to 29 per cent., respectively. There was no change at 6 mg. dieldrin/sq. ft. but the other treatments (12 and 25 mg. dieldrin and 12, 25 and 50 mg. chlordane/sq. ft.) had improved. Dieldrin at 12 and 25 mg./sq. ft. and chlordane at 50 mg./sq. ft. attained complete control.
The spray-volume treatments, now in their second year, showed an increase in activity. This was most marked in the wettable-powder treatments at 25 mg. p.p′DDT/sq. ft. which a year ago were completely ineffective and now five out of six trials gave complete control and the other 97 per cent. Improvement in the treatments at 50 mg./sq. ft. was less (from 43 to 83%) due in the main to the complete failure of one treatment (10 gal./acre).
It is confirmed that spray volume in itself is unimportant in larvicidal applications providing the coverage is adequate.
Field Trials of Larvicides against Culicoides with a Discussion on the Relationship Between Rainfall and Larval Control
- D. S. Kettle, R. H. Parish
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- Journal:
- Bulletin of Entomological Research / Volume 48 / Issue 2 / June 1957
- Published online by Cambridge University Press:
- 10 July 2009, pp. 425-434
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Further observations and trials were conducted with insecticides against larvae of Culicoides impunctatus Goetgh. on Soutra Hill, Midlothian. The analysis of the data was complicated by a large natural reduction (76%) which occurred in the untreated plots. Nevertheless, it appears that the following dosages of insecticidal preparation were still active two years after application:—(a) 50 and 200 mg. p,p′DDT/sq. ft. applied as a dust, wettable powder or water-miscible concentrate (99% control), (b) 50 and 200 mg. γ BHC/sq. ft. as a wettable powder or 200 mg. γ BHC/sq. ft. as a water-miscible concentrate (95% control), (c) dieldrin at 25 mg./sq. ft., which gave 97 per cent, control and (d) chlordane at 50 mg./sq. ft., which gave 84 per cent. control.
The effect of spray volume on insecticidal effect was investigated by applying 25 mg. and 50 mg. p,p′DDT/sq. ft. in the following spray volumes:—5, 10, 15, 25, 50 and 80 gals./acre. The effect of 50 mg./sq. ft. at each volume was less marked than in the previous work, when only one concentration was used. Weather conditions in the present season were unusual, but there were indications that moderate spray volumes (15 and 25 gals./acre) give the best results at this dosage of insecticide. The combined results for 50 mg./sq. ft. at all volumes gave only 43 per cent, residual control, while those for the lower dosage showed no residual control.
The results are discussed with reference to the effect of rainfall on residual control. It is concluded that the volume of spray applied is unimportant provided the droplets of insecticide are closely and evenly distributed on the mossy vegetation that overlies the peat. Subsequent prolonged rain, of the order of 20 inches, is required to attain the most effective distribution of the insecticide, which is at the surface of the peat, where the eggs are laid and the newly hatched larvae will come in contact with the poison.
Combined active and passive immunization against diphtheria
- A. W. Downie, A. T. Glenny, H. J. Parish, E. T. C. Spooner, R. L. Vollum, G. S. wilson
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- Journal:
- Journal of Hygiene / Volume 46 / Issue 1 / March 1948
- Published online by Cambridge University Press:
- 15 May 2009, pp. 34-41
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Three sets of experiments were carried out on undergraduate medical students at Oxford, Cambridge and Liverpool during the years 1941–4 in order to supplement the information obtained previously (Downie et al. 1941) on the comparative antitoxin response of those given active immunization alone (Group A) and those given combined active and passive immunization (Group A+P). A summary of each of the experiments has already been given in the text, so that it is unnecessary here to do more than recapitulate briefly the main results.
1. The first experiment showed that in Group A the antitoxin response was not appreciably greater in students receiving doses of 0·3 and 0·3–0·5 ml. of A.P.T. at 4 weeks’ interval than in those receiving doses of only 0·1 and 0·3 ml. In Group A + P no difference was noticed in the antitoxin content of the serum 6–8 weeks after the second injection of A.P.T., but 10–12 weeks after the second injection there was a difference in favour of the students receiving the larger doses of A.P.T., though it was below the conventional level of statistical significance.
2. The second experiment showed that when the doses of A.P.T. were spaced by 2 instead of by 4 weeks the antitoxin response was much less in both the A and the A + P groups, though the difference was less in the latter group, particularly when the measurements were made 10–12 weeks after the second inoculation of A.P.T.
3. The third experiment showed that a dose of 5000 units of diphtheria antiserum given at the time of the first injection of A.P.T. inhibited antitoxin production to a greater extent than a dose of 400–500 units, though the difference was much less when the measurements were made at 12 weeks after the second inoculation than at 4 weeks.
A compilation of the results obtained during 1940–2 in groups of students receiving active and those receiving active plus passive immunization shows that the antitoxin production in the first group (Group A) was much higher than in the second group (Group A + P) 6–8 weeks after the second injection of A.P.T., but that 10–12 weeks after the second inoculation the difference, though still significant, was considerably less. The final Schick-test results at 10–12 weeks gave a Schick-conversion rate of 98.0% in Group A and of 90.9% in Group A + P.
A review of the results obtained during the years 1939–44 on about 450 students at Oxford, Sheffield and Liverpool leads to the conclusion that the effect of giving diphtheria antiserum at the time of the first injection of A.P.T. is to cause a delay and some degree of inhibition in the antitoxin response of the subject. The larger the amount of antiserum given, the greater is this effect. With a dose of 500 units, though the delay in antitoxin formation is very obvious 4 weeks after the second injection of A.P.T., the final degree of immunity attained, as judged by the antitoxin concentration of the blood serum and by the Schick-conversion rate, is not greatly inferior to that resulting from active immunization alone; and even with a dose of 5000 units, the Schick-conversion rate reaches 81 % 12 weeks after the second injection of A.P.T. It is clear, therefore, that the antiserum, even when given in a dose as large as 5000 units, does not neutralize more than a small part of the antigenic activity of the first dose of A.P.T. Its main effect is apparently to diminish the rate of sensitization of the tissues, so that when a second dose of A.P.T. is given 4 weeks later, the rise in the antitoxin content of the blood serum is considerably delayed. Our experiments suggest that by increasing the size of the first dose of A.P.T., some of this delay may be avoided.
The partial neutralization of the first dose of A.P.T. will result in a decrease in the total antigenic stimulus and a delay in the time at which ït comes into operation. It is suggested that, provided the tissues have not been previously sensitized to diphtheria toxin, the result may be that the two doses will act virtually as a single dose. Such an explanation, however, must remain unproven till further observations have been made (see p. 35).
The practical value of combined active and passive immunization, especially when joined with temporary segregation of healthy carriers, in combating outbreaks of diphtheria in schools and other institutions for children has been clearly shown by Fulton, Taylor, Wells & Wilson (1941). Our present experiments lead us to suggest that, when applying the method in practice, it would be wise to give an initial dose of 0·5 ml. of A.P.T., together with 500 units of diphtheria antiserum injected at a different site, followed 6 weeks later by a second dose of 0.5 ml. A.P.T. It is probable that children treated in this way will develop approximately the same ultimate degree of immunity as those actively immunized with doses of 0·3 and 0·5 ml. of A.P.T. at 4 weeks’ interval.
We should like to express our thanks to Prof. A. D. Gardner and Prof. H. R. Dean for permitting observations to be made on the students in the pathology classes at Oxford and Cambridge; and to the students themselves at Oxford, Cambridge and Liverpool, for their ready co-operation in the inquiry.
Large Area 6H- and 4H-SiC Photoconductive Switches
- S. Doğan, F. Yun, C.B. Roberts, J. Parish, D. Huang, R. E. Myers, M. Smith, S. E Saddow, B. Ganguly, H. Morkoç
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- Journal:
- MRS Online Proceedings Library Archive / Volume 764 / 2003
- Published online by Cambridge University Press:
- 01 February 2011, C7.2
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- 2003
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Photoconductive Semiconductor Switches (PCSS) were fabricated in planar structures on high resistivity 4H-SiC and conductive 6H-SiC and tested at DC Bias voltages up to 1000 V. The gap spacing between the electrodes is 1 mm. The average on-state resistance and the ratio of on-state to off-state currents were about 20 Ω and 3×1011 for 4H-SiC, and 60 Ω and 6.6×103 for 6H-SiC, respectively. The typical maximum switch current at 1000 V is about 49 A for 4H-SiC. Photoconductivity pulse widths for all applied voltages were 8-10 ns. The observed performance is due in part to the removal of the surface damage by high temperature H2 etching and surface preparation. Atomic Force Microscopy (AFM) images revealed that very good surface morphology, atomic layer flatness and large step widths were achieved with this surface treatment and these atomically smooth surfaces likely contributed to the excellent switching performance of these devices.
Dispersion of Ceramic Particles in Organic Liquids
- P. D. Calvert, R. R. Lalanandham, M. V. Parish, J. Fox, H. Lee, R. L. Pober, E. S. Tormey, H. K. Bowen
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- Journal:
- MRS Online Proceedings Library Archive / Volume 73 / 1986
- Published online by Cambridge University Press:
- 28 February 2011, 579
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- 1986
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Good dispersion of oxide ceramics in organic solvents can be achieved using many different dispersants. Several types of dispersants, including fatty acids, coupling agents, polar aromatic compounds and polymers, are discussed to illustrate the important phenomena. Many new problems arise in actual slips during ceramics processing; these are briefly discussed.